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Estradiol is an oral hormone used to reduce the symptoms of menopause. Used for brittle bones (osteoporosis), and to treat certain cancers in both men and women, Estradiol is a hormone. It is given to women who no longer produce the proper amount. It is used to reduce menopause side effects such as hot flashes, feelings of warmth in the face, neck and chest and/or dry, itchy external genitals and vaginal irritation.)

Estradiol Prescribed
May be taken with food or immediately after a meal to prevent stomach upset. Take this medication as prescribed. Follow the dosing schedule carefully. Be sure to ask your doctor if you have any questions.

Adverse Events
The adverse effects associated with the use of Estradiol are dizziness, bloating, lightheadedness, headache, stomach upset, or nausea. The side effects should diminish as your body adjusts to Estradiol. Notify your physician if you experience any of the following: severe depression, calf pain, sudden severe headache, chest pain, shortness of breath, lumps in the breast, weakness or tingling in the arms or legs, yellowing of the eyes or skin, changes in vaginal bleeding (spotting, breakthrough bleeding, prolonged or complete stoppage of bleeding), stomach pain, skin rash. If you notice other effects not listed above, contact your doctor or pharmacist.

Warnings
Report your entire medical history to your physician before taking Estradiol, including: family medical history (especially breast lumps and cancer), migraine headaches, liver disease, heart disease, kidney disease, depression, high blood pressure, diabetes, asthma, epilepsy (seizures), toxemia (high blood pressure during pregnancy), jaundice (yellowing skin/eyes) during pregnancy, excessive weight gain and fluid retention (bloating) during menstrual cycle, uterine fibroid tumor, abnormal vaginal bleeding, blood clots or stroke, cholesterol or lipid problems, gallbladder disease. Before having surgery, tell the doctor that you take this drug. Depending on strength, this drug may cause a patchy, darkening of the skin on the face (melasma). Higher strengths are more likely to cause melasma. Sunlight may intensify this darkening and you may need to avoid prolonged sun exposure and sunlamps. Consult your physician regarding use of sunscreens and protective clothing. Cigarette smoking can increase the chance of blood-clots while taking this medication (especially in women past the age of 35). This drug should not be used during pregnancy. If you become pregnant or think you may be pregnant, inform your doctor immediately. This drug may be excreted into breast milk and its use is not recommended while breast-feeding. Consult your doctor before breast-feeding.

Notify your physician of all prescription and nonprescription drugs that you use, especially of: hydantoins (e.g., phenytoin), barbiturates (e.g., phenobarbital), corticosteroids (e.g., prednisone). This product can affect the results of certain lab tests. Make sure laboratory personnel and your doctors know you use this drug. Do not start or stop any medicine without doctor or pharmacist approval.


Special Notes
Follow the usage information instructed by your physician. The information is intended to supplement, not substitute for, the expertise and judgment of your doctor, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your medical provider before Estradiol.

If an overdose of Estradiol is suspected, contact your emergency room immediately. Symptoms of overdose may include nausea/vomiting or stoppage of periods.
Do not share Estradiol with others who it is not prescribed. If you miss a dose of Estradiol, take it as soon as remembered. Do not take Estradiol if it is almost time for the next scheduled dose. Do not "double-up" the dose to catch up.